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Changes in skin tone, if any, are gradual and may take several weeks or months of consistent use to show noticeable effects

The purpose of this is to promote ketone body production (acetone, beta-hydroxybutyrate, acetoacetate) to be used as a fuel source as opposed to glucose impacting the microbiome and host metabolism (197)

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128 Diabetic mice with hepatocyte-specific deletion of PPAR had improved hepatic steatosis yet more severe IR, probably due to reduced insulin sensitivity in muscle and adipose tissues